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RDIF says AstraZeneca, Sputnik Light jab match found to be safe

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Moscow, Feb 14 (Prensa Latina) The Russian Direct Investment Fund (RDIF) on Monday reported the early results from world´s first mix-match joint clinical trials of Sputnik Light and AstraZeneca Covid-19 jabs in Russia and Azerbaijan has proven full safety of the combination, with no serious adverse events reported.

According to the Phase-2 interim results of the trials, involving 100 volunteers in Russia and 100 volunteers in Azerbaijan, the vaccines combination demonstrated an acceptable safety profile, which is consistent with the results of previous AstraZeneca vaccine, Sputnik V and Sputnik Light vaccines clinical trials, the statement noted.

It´s noted that the monitoring of the volunteers continued for 57 days following the administration of the first dose and demonstrated a good safety profile of the combined use of two jabs. No serious adverse events related to immunization were observed, the RDIF noted.

In a joint effort, the RDIF, the Gamaleya Center, AstraZeneca and R-Pharm were the first worldwide to launch a program of clinical trials evaluating the combined use of various adenovirus-based vaccines for the prevention of the coronavirus infection.

In December 2021, the World Health Organization (WHO) recommended a similar approach, also known as heterologous prime booster vaccination, for use in actual clinical practice.

According to the WHO, heterologous vaccination schedules with different jabs allow for greater flexibility of vaccination programs making them more accessible as well as increase the effectiveness of inoculation.

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