The technological platform of this vaccine candidate -developed by the Finlay Vaccine Institute (IFV)- is based on macromolecular constructions with a recombinant receptor-binding domain (RBD) conjugated with tetanus toxoid (TT) and induces a powerful immune response in lab animals.
The US magazine, belonging to the American Chemical Society, noted among the advantages of immunization with RBD-TT conjugates a predominant IgG immunoglobulin defense due to affinity maturation and specific long-term memory B cells (lymphocytes).
In this regard, PhD in Sciences Dagmar García, IFV’s Research Director, specified on Facebook that she sent the article on April 11, 2020, and its publication revealed that it took three months for arbitration, review, correction and disclosure. ‘It is an excellent example that summarizes the collaboration of scientists from various Cuban and foreign institutions, who have been a great team in this year of hard work to enforce the science we do in Cuba,’ Garcia stated.
pgh/Pll/oda / nmr